SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication.

Neuvonen, Maarit; Kazlauskas, Arunas; Martikainen, Miika; Hinkkanen, Ari; Ahola, Tero; Saksela, Kalle

Neuvonen, Maarit; Kazlauskas, Arunas; Martikainen, Miika; Hinkkanen, Ari; Ahola, Tero; Saksela, Kalle.

Affiliation

Neuvonen M; Institute of Biotechnology, University of Helsinki, Helsinki, Finland.

PLoS Pathog ; 7(11): e1002383, 2011 Nov.

Article in En | MEDLINE | ID: mdl-22114558

Subject(s)

Alphavirus/metabolism; Nerve Tissue Proteins/metabolism; RNA, Viral/biosynthesis; Viral Nonstructural Proteins/metabolism; Virus Replication/genetics; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Chikungunya virus/genetics; HeLa Cells; Humans; Ligands; Mice; Semliki forest virus/genetics; Sindbis Virus/genetics; src Homology Domains/genetics

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Full text: 1 Database: MEDLINE Main subject: Virus Replication / RNA, Viral / Viral Nonstructural Proteins / Alphavirus / Nerve Tissue Proteins Limits: Animals / Humans Language: En Journal: PLoS Pathog Year: 2011 Type: Article Affiliation country: Finland

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