Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens.

Jog, Neelakshi R; Frisoni, Lorenza; Shi, Qin; Monestier, Marc; Hernandez, Sairy; Craft, Joe; Prak, Eline T Luning; Caricchio, Roberto

Jog, Neelakshi R; Frisoni, Lorenza; Shi, Qin; Monestier, Marc; Hernandez, Sairy; Craft, Joe; Prak, Eline T Luning; Caricchio, Roberto.

Affiliation

Jog NR; Temple University, Philadelphia, Pennsylvania 19140, USA.

Arthritis Rheum ; 64(4): 1247-56, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22127758

Subject(s)

Antibodies, Antinuclear/immunology; Apoptosis/immunology; Autoantigens/immunology; Deoxyribonucleases/metabolism; Lupus Erythematosus, Systemic/immunology; Animals; Cell Nucleus/immunology; Disease Models, Animal; Immune Tolerance/immunology; Lupus Erythematosus, Systemic/metabolism; Mice

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Full text: 1 Database: MEDLINE Main subject: Autoantigens / Antibodies, Antinuclear / Apoptosis / Deoxyribonucleases / Lupus Erythematosus, Systemic Limits: Animals Language: En Journal: Arthritis Rheum Year: 2012 Type: Article Affiliation country: United States

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