Chromosome breakage in human preimplantation embryos from carriers of structural chromosomal abnormalities in relation to fragile sites, maternal age, and poor sperm factors.

Xanthopoulou, L; Ghevaria, H; Mantzouratou, A; Serhal, P; Doshi, A; Delhanty, J D A

Xanthopoulou, L; Ghevaria, H; Mantzouratou, A; Serhal, P; Doshi, A; Delhanty, J D A.

Affiliation

Xanthopoulou L; UCL Centre for PGD, Institute for Women's Health, University College London, London, UK. l.xanthopoulou@ucl.ac.uk

Cytogenet Genome Res ; 136(1): 21-9, 2012.

Article in En | MEDLINE | ID: mdl-22179562

Subject(s)

Blastocyst/physiology; Blastocyst/ultrastructure; Chromosome Breakage; Chromosome Fragile Sites; Heterozygote; Maternal Age; Spermatozoa/pathology; Adult; Blastomeres/metabolism; Blastomeres/pathology; Embryo Transfer/methods; Female; Follow-Up Studies; Genetic Testing; Humans; Male; Middle Aged; Pregnancy; Preimplantation Diagnosis/methods; Reproductive History; Sex Factors; Spermatozoa/metabolism

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Full text: 1 Database: MEDLINE Main subject: Spermatozoa / Blastocyst / Maternal Age / Chromosome Breakage / Chromosome Fragile Sites / Heterozygote Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged / Pregnancy Language: En Journal: Cytogenet Genome Res Journal subject: GENETICA Year: 2012 Type: Article Affiliation country: United kingdom

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