Lysosomal signaling enhances mitochondria-mediated photodynamic therapy in A431 cancer cells: role of iron.

Saggu, Shalini; Hung, Hsin-I; Quiogue, Geraldine; Lemasters, John J; Nieminen, Anna-Liisa

Saggu, Shalini; Hung, Hsin-I; Quiogue, Geraldine; Lemasters, John J; Nieminen, Anna-Liisa.

Affiliation

Saggu S; Department of Pharmaceutical and Biomedical Sciences, Center for Cell Death, Injury and Regeneration, Medical University of South Carolina, Charleston, SC, USA.

Photochem Photobiol ; 88(2): 461-8, 2012.

Article in En | MEDLINE | ID: mdl-22220628

Subject(s)

Carcinoma, Squamous Cell/drug therapy; Indoles/pharmacology; Lysosomes/metabolism; Mitochondria/metabolism; Photochemotherapy; Photosensitizing Agents/pharmacology; Apoptosis/drug effects; Apoptosis/radiation effects; Carcinoma, Squamous Cell/pathology; Cell Line, Tumor; Cell Survival/drug effects; Cell Survival/radiation effects; Enzyme Inhibitors/pharmacology; Humans; Iron/metabolism; Iron Chelating Agents/pharmacology; Isoindoles; Light; Lysosomes/drug effects; Lysosomes/radiation effects; Macrolides/pharmacology; Mitochondria/drug effects; Mitochondria/radiation effects; Signal Transduction/drug effects; Signal Transduction/radiation effects; Vacuolar Proton-Translocating ATPases/antagonists & inhibitors; Vacuolar Proton-Translocating ATPases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Photochemotherapy / Carcinoma, Squamous Cell / Photosensitizing Agents / Indoles / Lysosomes / Mitochondria Limits: Humans Language: En Journal: Photochem Photobiol Year: 2012 Type: Article Affiliation country: United States

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