A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.

Phadwal, Kanchan; Alegre-Abarrategui, Javier; Watson, Alexander Scarth; Pike, Luke; Anbalagan, Selvakumar; Hammond, Ester M; Wade-Martins, Richard; McMichael, Andrew; Klenerman, Paul; Simon, Anna Katharina

Phadwal, Kanchan; Alegre-Abarrategui, Javier; Watson, Alexander Scarth; Pike, Luke; Anbalagan, Selvakumar; Hammond, Ester M; Wade-Martins, Richard; McMichael, Andrew; Klenerman, Paul; Simon, Anna Katharina.

Affiliation

Phadwal K; BRC Translational Immunology Laboratory, National Institute for Health Research, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford UK.

Autophagy ; 8(4): 677-89, 2012 Apr.

Article in En | MEDLINE | ID: mdl-22302009

Subject(s)

Autophagy/immunology; Biological Assay/methods; Cellular Senescence/immunology; T-Lymphocytes/cytology; T-Lymphocytes/immunology; Adult; Animals; B-Lymphocytes/cytology; B-Lymphocytes/immunology; Cells, Cultured; HEK293 Cells; Histones/metabolism; Humans; Mice; Middle Aged; Reproducibility of Results

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Full text: 1 Database: MEDLINE Main subject: Autophagy / Biological Assay / T-Lymphocytes / Cellular Senescence Type of study: Diagnostic_studies Limits: Adult / Animals / Humans / Middle aged Language: En Journal: Autophagy Year: 2012 Type: Article

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