Discovery of 3,4-dihydropyrimidin-2(1H)-ones with inhibitory activity against HIV-1 replication.

Kim, Junwon; Park, Changmin; Ok, Taedong; So, Wonyoung; Jo, Mina; Seo, Minjung; Kim, Youngmi; Sohn, Jeong-Hun; Park, Youngsam; Ju, Moon Kyeong; Kim, Junghwan; Han, Sung-Jun; Kim, Tae-Hee; Cechetto, Jonathan; Nam, Jiyoun; Sommer, Peter; No, Zaesung

Kim, Junwon; Park, Changmin; Ok, Taedong; So, Wonyoung; Jo, Mina; Seo, Minjung; Kim, Youngmi; Sohn, Jeong-Hun; Park, Youngsam; Ju, Moon Kyeong; Kim, Junghwan; Han, Sung-Jun; Kim, Tae-Hee; Cechetto, Jonathan; Nam, Jiyoun; Sommer, Peter; No, Zaesung.

Affiliation

Kim J; Medicinal Chemistry Group, Institut Pasteur Korea (IP-K), Sampyeong-dong 696, Bundang-gu, Seongnam-si, Gyeonggi-do 463-400, Republic of Korea.

Bioorg Med Chem Lett ; 22(5): 2119-24, 2012 Mar 01.

Article in En | MEDLINE | ID: mdl-22305583

Subject(s)

Anti-HIV Agents/chemistry; Anti-HIV Agents/pharmacology; HIV-1/drug effects; Pyrimidinones/chemistry; Pyrimidinones/pharmacology; Virus Replication/drug effects; Drug Design; HIV Infections/drug therapy; Humans; Stereoisomerism; Structure-Activity Relationship

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Full text: 1 Database: MEDLINE Main subject: Pyrimidinones / Virus Replication / HIV-1 / Anti-HIV Agents Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Type: Article

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