Potentiation of anticancer drugs: effects of pentoxifylline on neoplastic cells.

Barancik, Miroslav; Bohacova, Viera; Gibalova, Lenka; Sedlak, Jan; Sulova, Zdena; Breier, Albert

Barancik, Miroslav; Bohacova, Viera; Gibalova, Lenka; Sedlak, Jan; Sulova, Zdena; Breier, Albert.

Affiliation

Barancik M; Institute for Heart Research, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava 840 05, Slovakia.

Int J Mol Sci ; 13(1): 369-82, 2012.

Article in En | MEDLINE | ID: mdl-22312258

Subject(s)

Antineoplastic Agents/toxicity; Drug Resistance, Neoplasm/drug effects; Pentoxifylline/toxicity; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Animals; Apoptosis/drug effects; Caspase 3/metabolism; Caspase 9/metabolism; Cell Line, Tumor; Down-Regulation/drug effects; Matrix Metalloproteinases/metabolism; Mice; Phosphorylation/drug effects; Proto-Oncogene Proteins c-akt/metabolism; Vincristine/toxicity

Key words

P-glycoprotein; apoptosis; caspases; matrix metalloproteinases; multidrug resistance; pentoxifylline

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Full text: 1 Database: MEDLINE Main subject: Pentoxifylline / Drug Resistance, Neoplasm / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Mol Sci Year: 2012 Type: Article Affiliation country: Slovakia

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