Functional analysis of VPS41-mediated neuroprotection in Caenorhabditis elegans and mammalian models of Parkinson's disease.

Harrington, Adam J; Yacoubian, Talene A; Slone, Sunny R; Caldwell, Kim A; Caldwell, Guy A

Harrington, Adam J; Yacoubian, Talene A; Slone, Sunny R; Caldwell, Kim A; Caldwell, Guy A.

Affiliation

Harrington AJ; Department of Biological Sciences, The University of Alabama, Tuscaloosa, Alabama 35487, USA.

J Neurosci ; 32(6): 2142-53, 2012 Feb 08.

Article in En | MEDLINE | ID: mdl-22323726

Subject(s)

Caenorhabditis elegans Proteins/physiology; Caenorhabditis elegans/physiology; Neuroprotective Agents/metabolism; Parkinson Disease/metabolism; Parkinson Disease/prevention & control; Protein Multimerization; Vesicular Transport Proteins/physiology; Animals; Animals, Genetically Modified; Cell Line, Tumor; DNA-Binding Proteins/genetics; Disease Models, Animal; Gene Knockout Techniques; Genetic Predisposition to Disease; Humans; Parkinson Disease/genetics; Transcription Factors/genetics; alpha-Synuclein/metabolism

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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Caenorhabditis elegans / Neuroprotective Agents / Caenorhabditis elegans Proteins / Vesicular Transport Proteins / Protein Multimerization Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Neurosci Year: 2012 Type: Article Affiliation country: United States

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