Targeted proteomics of the eicosanoid biosynthetic pathway completes an integrated genomics-proteomics-metabolomics picture of cellular metabolism.

Sabidó, Eduard; Quehenberger, Oswald; Shen, Qin; Chang, Ching-Yun; Shah, Ishita; Armando, Aaron M; Andreyev, Alexander; Vitek, Olga; Dennis, Edward A; Aebersold, Ruedi

Sabidó, Eduard; Quehenberger, Oswald; Shen, Qin; Chang, Ching-Yun; Shah, Ishita; Armando, Aaron M; Andreyev, Alexander; Vitek, Olga; Dennis, Edward A; Aebersold, Ruedi.

Affiliation

Sabidó E; Department of Biology, Institute of Molecular Systems Biology and Competence Center for Systems Physiology and Metabolic Disease, ETH Zurich, 8093 Zurich, Switzerland.

Mol Cell Proteomics ; 11(7): M111.014746, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22361236

Subject(s)

Arachidonic Acid/metabolism; Biosynthetic Pathways/drug effects; Eicosanoids/biosynthesis; Inflammation/metabolism; Macrophages/metabolism; Adenosine Triphosphate/pharmacology; Animals; Cell Line; Inflammation/chemically induced; Lipid Metabolism/drug effects; Lipopolysaccharides/pharmacology; Macrophages/drug effects; Mass Spectrometry; Metabolomics; Mice; Proteomics; Signal Transduction/drug effects

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Full text: 1 Database: MEDLINE Main subject: Eicosanoids / Arachidonic Acid / Biosynthetic Pathways / Inflammation / Macrophages Limits: Animals Language: En Journal: Mol Cell Proteomics Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2012 Type: Article Affiliation country: Switzerland

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