SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells.

Wang, Ying; Zhu, Zhou; Church, Tony D; Lugogo, Njira L; Que, Loretta G; Francisco, Dave; Ingram, Jennifer L; Huggins, Molly; Beaver, Denise M; Wright, Jo Rae; Kraft, Monica

Wang, Ying; Zhu, Zhou; Church, Tony D; Lugogo, Njira L; Que, Loretta G; Francisco, Dave; Ingram, Jennifer L; Huggins, Molly; Beaver, Denise M; Wright, Jo Rae; Kraft, Monica.

Affiliation

Wang Y; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. ying.wang5@duke.edu

J Immunol ; 188(7): 3371-81, 2012 Apr 01.

Article in En | MEDLINE | ID: mdl-22371396

Subject(s)

Asthma/enzymology; Epithelial Cells/immunology; Mycoplasma pneumoniae/immunology; Protein Tyrosine Phosphatase, Non-Receptor Type 6/physiology; Adult; Asthma/immunology; Asthma/physiopathology; Bronchoalveolar Lavage Fluid/cytology; Cell Nucleus/enzymology; Cells, Cultured/enzymology; Cells, Cultured/immunology; Epithelial Cells/enzymology; Female; Humans; In Vitro Techniques; Inflammation; Interleukin-8/biosynthesis; Interleukin-8/genetics; Male; NF-kappa B/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatase, Non-Receptor Type 6/antagonists & inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 6/genetics; Proto-Oncogene Proteins c-akt/metabolism; RNA Interference; RNA, Small Interfering/pharmacology; Transcription, Genetic; Young Adult

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Full text: 1 Database: MEDLINE Main subject: Asthma / Epithelial Cells / Protein Tyrosine Phosphatase, Non-Receptor Type 6 / Mycoplasma pneumoniae Limits: Adult / Female / Humans / Male Language: En Journal: J Immunol Year: 2012 Type: Article Affiliation country: United States

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