Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.

Nilsson, Lisa M; Forshell, Tacha Zi Plym; Rimpi, Sara; Kreutzer, Christiane; Pretsch, Walter; Bornkamm, Georg W; Nilsson, Jonas A

Nilsson, Lisa M; Forshell, Tacha Zi Plym; Rimpi, Sara; Kreutzer, Christiane; Pretsch, Walter; Bornkamm, Georg W; Nilsson, Jonas A.

Affiliation

Nilsson LM; Department of Molecular Biology, Umeå University, Umeå, Sweden. jonas.a.nilsson@surgery.gu.se

PLoS Genet ; 8(3): e1002573, 2012.

Article in En | MEDLINE | ID: mdl-22438825

Subject(s)

Glycine Hydroxymethyltransferase; L-Lactate Dehydrogenase; Lymphoma, B-Cell/metabolism; Phosphoglycerate Dehydrogenase; Proto-Oncogene Proteins c-myc/genetics; Proto-Oncogene Proteins c-myc/metabolism; Adenomatous Polyposis Coli Protein/genetics; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, ras/genetics; Glycine Hydroxymethyltransferase/genetics; Glycine Hydroxymethyltransferase/metabolism; Humans; Isoenzymes/genetics; Isoenzymes/metabolism; L-Lactate Dehydrogenase/genetics; L-Lactate Dehydrogenase/metabolism; Lactate Dehydrogenase 5; Lymphoma, B-Cell/genetics; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Transgenic; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Phosphoglycerate Dehydrogenase/genetics; Phosphoglycerate Dehydrogenase/metabolism; Tumor Suppressor Protein p53/genetics

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Full text: 1 Database: MEDLINE Main subject: Glycine Hydroxymethyltransferase / Lymphoma, B-Cell / Proto-Oncogene Proteins c-myc / Phosphoglycerate Dehydrogenase / L-Lactate Dehydrogenase Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2012 Type: Article Affiliation country: Sweden

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