Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver.

Satapati, Santhosh; Sunny, Nishanth E; Kucejova, Blanka; Fu, Xiaorong; He, Tian Teng; Méndez-Lucas, Andrés; Shelton, John M; Perales, Jose C; Browning, Jeffrey D; Burgess, Shawn C

Satapati, Santhosh; Sunny, Nishanth E; Kucejova, Blanka; Fu, Xiaorong; He, Tian Teng; Méndez-Lucas, Andrés; Shelton, John M; Perales, Jose C; Browning, Jeffrey D; Burgess, Shawn C.

Affiliation

Satapati S; Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

J Lipid Res ; 53(6): 1080-92, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22493093

Subject(s)

Citric Acid Cycle; Diet, High-Fat/adverse effects; Fatty Liver/metabolism; Fatty Liver/pathology; Insulin Resistance; Animals; Cell Respiration; Fatty Liver/complications; Fatty Liver/etiology; Gluconeogenesis; Hyperglycemia/complications; Ketone Bodies/biosynthesis; Liver/metabolism; Liver/pathology; Male; Mice; Mice, Inbred C57BL; Mitochondria/metabolism; Mitochondria/pathology; Obesity/complications; Oxidative Stress; Time Factors

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Full text: 1 Database: MEDLINE Main subject: Insulin Resistance / Citric Acid Cycle / Fatty Liver / Diet, High-Fat Type of study: Etiology_studies Limits: Animals Language: En Journal: J Lipid Res Year: 2012 Type: Article Affiliation country: United States

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