Loss of cytoskeletal transport during egress critically attenuates ectromelia virus infection in vivo.

Lynn, Helena; Horsington, Jacquelyn; Ter, Lee Kuan; Han, Shuyi; Chew, Yee Lian; Diefenbach, Russell J; Way, Michael; Chaudhri, Geeta; Karupiah, Gunasegaran; Newsome, Timothy P

Lynn, Helena; Horsington, Jacquelyn; Ter, Lee Kuan; Han, Shuyi; Chew, Yee Lian; Diefenbach, Russell J; Way, Michael; Chaudhri, Geeta; Karupiah, Gunasegaran; Newsome, Timothy P.

Affiliation

Lynn H; School of Molecular Bioscience, University of Sydney, Sydney, NSW, Australia.

J Virol ; 86(13): 7427-43, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22532690

Subject(s)

Cytoskeletal Proteins/metabolism; Ectromelia virus/pathogenicity; Ectromelia, Infectious/virology; Host-Pathogen Interactions; Viral Proteins/metabolism; Virus Release; Animals; Ectromelia virus/genetics; Female; Gene Deletion; Liver/virology; Lymph Nodes/virology; Mice; Mice, Inbred BALB C; Protein Transport; Spleen/virology; Viral Load; Viral Plaque Assay; Viral Proteins/genetics; Virulence

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Full text: 1 Database: MEDLINE Main subject: Viral Proteins / Ectromelia, Infectious / Cytoskeletal Proteins / Ectromelia virus / Host-Pathogen Interactions / Virus Release Limits: Animals Language: En Journal: J Virol Year: 2012 Type: Article Affiliation country: Australia

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