Amplification of Toll-like receptor-mediated signaling through spleen tyrosine kinase in human B-cell activation.

Iwata, Shigeru; Yamaoka, Kunihiro; Niiro, Hiroaki; Nakano, Kazuhisa; Wang, Sheau-Pey; Akashi, Koichi; Tanaka, Yoshiya

Iwata, Shigeru; Yamaoka, Kunihiro; Niiro, Hiroaki; Nakano, Kazuhisa; Wang, Sheau-Pey; Akashi, Koichi; Tanaka, Yoshiya.

Affiliation

Iwata S; First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

J Allergy Clin Immunol ; 129(6): 1594-601.e2, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22541243

Subject(s)

B-Lymphocytes/enzymology; B-Lymphocytes/immunology; Intracellular Signaling Peptides and Proteins/metabolism; Lymphocyte Activation/immunology; Protein-Tyrosine Kinases/metabolism; Signal Transduction; Toll-Like Receptors/metabolism; B-Lymphocyte Subsets/immunology; B-Lymphocyte Subsets/metabolism; B-Lymphocytes/cytology; CD40 Antigens/metabolism; Cell Cycle; Cell Differentiation/immunology; Cytokines/biosynthesis; Humans; Immunologic Memory; Receptors, Antigen, B-Cell/metabolism; Syk Kinase; TNF Receptor-Associated Factor 6/metabolism; Toll-Like Receptor 9/metabolism

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Full text: 1 Database: MEDLINE Main subject: Protein-Tyrosine Kinases / B-Lymphocytes / Lymphocyte Activation / Signal Transduction / Intracellular Signaling Peptides and Proteins / Toll-Like Receptors Limits: Humans Language: En Journal: J Allergy Clin Immunol Year: 2012 Type: Article Affiliation country: Japan

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