Structures of YAP protein domains reveal promising targets for development of new cancer drugs.

Sudol, Marius; Shields, Denis C; Farooq, Amjad

Sudol, Marius; Shields, Denis C; Farooq, Amjad.

Affiliation

Sudol M; Laboratory of Signal Transduction and Proteomic Profiling, Weis Center for Research, Geisinger Clinic, Danville, PA 17821, USA. msudol1@geisinger.edu

Semin Cell Dev Biol ; 23(7): 827-33, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22609812

Subject(s)

Adaptor Proteins, Signal Transducing/chemistry; Antineoplastic Agents/therapeutic use; Neoplasms/drug therapy; Neoplasms/metabolism; Nuclear Proteins/chemistry; Nuclear Proteins/metabolism; Phosphoproteins/chemistry; Adaptor Proteins, Signal Transducing/metabolism; Animals; Drug Design; Humans; Molecular Targeted Therapy; Phosphoproteins/metabolism; Protein Folding; Signal Transduction/drug effects; Transcription Factors; YAP-Signaling Proteins

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Full text: 1 Database: MEDLINE Main subject: Phosphoproteins / Nuclear Proteins / Adaptor Proteins, Signal Transducing / Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Semin Cell Dev Biol Journal subject: EMBRIOLOGIA Year: 2012 Type: Article Affiliation country: United States

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