Heparan sulfate dissociates serum amyloid A (SAA) from acute-phase high-density lipoprotein, promoting SAA aggregation.

Noborn, Fredrik; Ancsin, John B; Ubhayasekera, Wimal; Kisilevsky, Robert; Li, Jin-Ping

Noborn, Fredrik; Ancsin, John B; Ubhayasekera, Wimal; Kisilevsky, Robert; Li, Jin-Ping.

Affiliation

Noborn F; Department of Medical Biochemistry and Microbiology, The Biomedical Center, Husargatan 3, Box 582, Uppsala University, 751 23 Uppsala, Sweden.

J Biol Chem ; 287(30): 25669-77, 2012 Jul 20.

Article in En | MEDLINE | ID: mdl-22654109

Subject(s)

Amyloidosis/metabolism; Apolipoprotein A-I; Heparitin Sulfate; Lipoproteins, HDL; Serum Amyloid A Protein; Amyloidosis/etiology; Animals; Apolipoprotein A-I/chemistry; Apolipoprotein A-I/metabolism; Heparitin Sulfate/chemistry; Heparitin Sulfate/metabolism; Lipoproteins, HDL/chemistry; Lipoproteins, HDL/metabolism; Mice; Serum Amyloid A Protein/chemistry; Serum Amyloid A Protein/metabolism; Surface Plasmon Resonance

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Full text: 1 Database: MEDLINE Main subject: Serum Amyloid A Protein / Apolipoprotein A-I / Heparitin Sulfate / Amyloidosis / Lipoproteins, HDL Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2012 Type: Article Affiliation country: Sweden

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