A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.

Yan, Zhijiang; Guo, Rong; Paramasivam, Manikandan; Shen, Weiping; Ling, Chen; Fox, David; Wang, Yucai; Oostra, Anneke B; Kuehl, Julia; Lee, Duck-Yeon; Takata, Minoru; Hoatlin, Maureen E; Schindler, Detlev; Joenje, Hans; de Winter, Johan P; Li, Lei; Seidman, Michael M; Wang, Weidong

Yan, Zhijiang; Guo, Rong; Paramasivam, Manikandan; Shen, Weiping; Ling, Chen; Fox, David; Wang, Yucai; Oostra, Anneke B; Kuehl, Julia; Lee, Duck-Yeon; Takata, Minoru; Hoatlin, Maureen E; Schindler, Detlev; Joenje, Hans; de Winter, Johan P; Li, Lei; Seidman, Michael M; Wang, Weidong.

Affiliation

Yan Z; Laboratory of Genetics, National Institute of Aging, National Institutes of Health, Baltimore, MD 21224, USA.

Mol Cell ; 47(1): 61-75, 2012 Jul 13.

Article in En | MEDLINE | ID: mdl-22705371

Subject(s)

DNA Repair; DNA-Binding Proteins/metabolism; Fanconi Anemia Complementation Group D2 Protein/metabolism; Fanconi Anemia Complementation Group Proteins/metabolism; Ubiquitination; Amino Acid Sequence; Animals; Cell Line, Tumor; DNA-Binding Proteins/genetics; Fanconi Anemia/genetics; Fanconi Anemia/metabolism; Fanconi Anemia Complementation Group D2 Protein/genetics; Fanconi Anemia Complementation Group Proteins/chemistry; Fanconi Anemia Complementation Group Proteins/genetics; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; HEK293 Cells; HeLa Cells; Humans; Immunoblotting; Lysine/chemistry; Lysine/genetics; Lysine/metabolism; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; RNA Interference; Sequence Homology, Amino Acid; Signal Transduction; Ubiquitin/metabolism; Ubiquitin-Protein Ligases/genetics; Ubiquitin-Protein Ligases/metabolism

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Full text: 1 Database: MEDLINE Main subject: DNA-Binding Proteins / DNA Repair / Fanconi Anemia Complementation Group Proteins / Fanconi Anemia Complementation Group D2 Protein / Ubiquitination Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2012 Type: Article Affiliation country: United States

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