Multiplex PCR for 17 Y-chromosome Specific Short Tandem Repeats (STR) to enhance the reliability of fetal sex determination in maternal plasma.

Rong, Yuan; Gao, Jiajia; Jiang, Xinqiang; Zheng, Fang

Rong, Yuan; Gao, Jiajia; Jiang, Xinqiang; Zheng, Fang.

Affiliation

Rong Y; Center for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Donghu Rd 169, Wuchang District, Wuhan 430071, China.
Gao J; Center for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Donghu Rd 169, Wuchang District, Wuhan 430071, China.
Jiang X; Institute of Forensic Science, Zhongnan Hospital of Wuhan University, Donghu Rd 169, Wuchang District, Wuhan 430071, China.
Zheng F; Center for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Donghu Rd 169, Wuchang District, Wuhan 430071, China.

Int J Mol Sci ; 13(5): 5972-5981, 2012.

Article in En | MEDLINE | ID: mdl-22754343

Subject(s)

Chromosomes, Human, Y/genetics; Multiplex Polymerase Chain Reaction/methods; Prenatal Diagnosis/methods; Sex Determination Analysis/methods; Amelogenin/genetics; Female; Humans; Male; Microsatellite Repeats; Pregnancy; Reagent Kits, Diagnostic; Reproducibility of Results

Key words

Y-chromosome specific STR; cell-free fetal DNA; gender determination; noninvasive prenatal diagnosis

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Full text: 1 Database: MEDLINE Main subject: Prenatal Diagnosis / Sex Determination Analysis / Chromosomes, Human, Y / Multiplex Polymerase Chain Reaction Type of study: Diagnostic_studies / Prognostic_studies Limits: Female / Humans / Male / Pregnancy Language: En Journal: Int J Mol Sci Year: 2012 Type: Article Affiliation country: China

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