7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove.

Ibarra-Soza, José M; Morris, Alexi A; Jayalath, Prasanna; Peacock, Hayden; Conrad, Wayne E; Donald, Michael B; Kurth, Mark J; Beal, Peter A

Ibarra-Soza, José M; Morris, Alexi A; Jayalath, Prasanna; Peacock, Hayden; Conrad, Wayne E; Donald, Michael B; Kurth, Mark J; Beal, Peter A.

Affiliation

Ibarra-Soza JM; Department of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, USA.

Org Biomol Chem ; 10(32): 6491-7, 2012 Aug 28.

Article in En | MEDLINE | ID: mdl-22766576

Subject(s)

Adenosine/chemistry; Aza Compounds/chemistry; Organophosphorus Compounds/chemistry; RNA, Small Interfering/chemistry; Ribonucleosides/chemistry; Adenosine/pharmacology; Aza Compounds/pharmacology; Drug Stability; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Organophosphorus Compounds/pharmacology; Protein Denaturation; RNA, Small Interfering/drug effects; Ribonucleosides/pharmacology; Temperature

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Organophosphorus Compounds / Ribonucleosides / Aza Compounds / Adenosine / RNA, Small Interfering Limits: Humans Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2012 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google