Tumor-initiating cells of various tumor types exhibit differential angiogenic properties and react differently to antiangiogenic drugs.

Benayoun, Liat; Gingis-Velitski, Svetlana; Voloshin, Tali; Segal, Ehud; Segev, Rotem; Munster, Michal; Bril, Rotem; Satchi-Fainaro, Ronit; Scherer, Stefan J; Shaked, Yuval

Benayoun, Liat; Gingis-Velitski, Svetlana; Voloshin, Tali; Segal, Ehud; Segev, Rotem; Munster, Michal; Bril, Rotem; Satchi-Fainaro, Ronit; Scherer, Stefan J; Shaked, Yuval.

Affiliation

Benayoun L; Department of Molecular Pharmacology, Technion, Haifa, Israel.

Stem Cells ; 30(9): 1831-41, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22782858

Subject(s)

Angiogenesis Inhibitors/pharmacology; Neoplasms/blood supply; Neoplasms/drug therapy; Neoplastic Stem Cells/drug effects; Animals; Cell Line, Tumor; Cell Survival/drug effects; Disease Models, Animal; HT29 Cells; Human Umbilical Vein Endothelial Cells/drug effects; Human Umbilical Vein Endothelial Cells/pathology; Humans; Immunoblotting; MCF-7 Cells; Mice; Mice, Nude; Neoplasms/pathology; Neoplastic Stem Cells/metabolism; Neoplastic Stem Cells/pathology; Neovascularization, Pathologic/drug therapy; Neovascularization, Pathologic/pathology; Transfection; Transplantation, Heterologous

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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Angiogenesis Inhibitors / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Stem Cells Year: 2012 Type: Article Affiliation country: Israel

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