High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia.

Luesink, Maaike; Hollink, Iris H I M; van der Velden, Vincent H J; Knops, Ruth H J N; Boezeman, Jan B M; de Haas, Valérie; Trka, Jan; Baruchel, Andre; Reinhardt, Dirk; van der Reijden, Bert A; van den Heuvel-Eibrink, Marry M; Zwaan, C Michel; Jansen, Joop H

Luesink, Maaike; Hollink, Iris H I M; van der Velden, Vincent H J; Knops, Ruth H J N; Boezeman, Jan B M; de Haas, Valérie; Trka, Jan; Baruchel, Andre; Reinhardt, Dirk; van der Reijden, Bert A; van den Heuvel-Eibrink, Marry M; Zwaan, C Michel; Jansen, Joop H.

Affiliation

Luesink M; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

Blood ; 120(10): 2064-75, 2012 Sep 06.

Article in En | MEDLINE | ID: mdl-22786876

Subject(s)

GATA2 Transcription Factor/genetics; Gene Expression; Leukemia, Myeloid, Acute/genetics; White People; Child; Child, Preschool; Female; GATA2 Transcription Factor/metabolism; Humans; Infant; Karyotyping; Leukemia, Myeloid, Acute/diagnosis; Leukemia, Myeloid, Acute/mortality; Male; Mutation; Oncogene Proteins, Fusion/genetics; Oncogene Proteins, Fusion/metabolism; Recurrence; Risk Factors; Sequence Analysis, DNA; Survival Analysis; Treatment Outcome; WT1 Proteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Gene Expression / White People / GATA2 Transcription Factor Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Blood Year: 2012 Type: Article Affiliation country: Netherlands

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