P300/CBP associated factor regulates nitroglycerin-dependent arterial relaxation by N(Îµ)-lysine acetylation of contractile proteins.

Colussi, Claudia; Scopece, Alessandro; Vitale, Serena; Spallotta, Francesco; Mattiussi, Stefania; Rosati, Jessica; Illi, Barbara; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca; Farsetti, Antonella; Capogrossi, Maurizio C; Gaetano, Carlo

Colussi, Claudia; Scopece, Alessandro; Vitale, Serena; Spallotta, Francesco; Mattiussi, Stefania; Rosati, Jessica; Illi, Barbara; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca; Farsetti, Antonella; Capogrossi, Maurizio C; Gaetano, Carlo.

Affiliation

Colussi C; Laboratorio di PatologiaVascolare, Istituto Dermopatico dell'Immacolata, Roma, Italy.

Arterioscler Thromb Vasc Biol ; 32(10): 2435-43, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22859492

Subject(s)

Actins/metabolism; Aorta/physiology; Lysine/metabolism; Myosin Light Chains/metabolism; Nitroglycerin/metabolism; Vasodilation/physiology; p300-CBP Transcription Factors/metabolism; Acetylation; Animals; Aorta/drug effects; Benzamides/pharmacology; Cyclic GMP/metabolism; Histone Deacetylase Inhibitors/pharmacology; Hydroxamic Acids/pharmacology; Injections, Subcutaneous; Male; Models, Animal; Muscle Contraction/drug effects; Muscle Contraction/physiology; Myocytes, Smooth Muscle/drug effects; Myocytes, Smooth Muscle/physiology; Nitroglycerin/administration & dosage; Nitroglycerin/pharmacology; Pyridines/pharmacology; Rats; Valproic Acid/pharmacology; p300-CBP Transcription Factors/drug effects

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Full text: 1 Database: MEDLINE Main subject: Aorta / Vasodilation / Actins / Nitroglycerin / Myosin Light Chains / P300-CBP Transcription Factors / Lysine Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2012 Type: Article Affiliation country: Italy

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