Probiotics in neonatology.
J Paediatr Child Health
; 48(9): 777-83, 2012 Sep.
Article
in En
| MEDLINE
| ID: mdl-22862675
ABSTRACT
Probiotics are micro-organisms that confer health benefits on the host. Postulated mechanisms include increasing resistance of the mucosal barrier to migration of bacteria and their toxins by strengthening intestinal cell junctions, modification of host response to microbial products, augmentation of immunoglobulin A mucosal responses, enhancement of enteral nutrition to inhibit the growth of pathogens; production of antimicrobial proteins; and competitive exclusion of potential pathogens. Published meta-analyses and systematic reviews report the effects of probiotics on important clinical outcomes in neonates. This paper will review the evidence for probiotic supplementation in neonatology, with a focus on preterm infants.
Full text:
1
Database:
MEDLINE
Main subject:
Probiotics
/
Neonatology
Limits:
Humans
/
Newborn
Language:
En
Journal:
J Paediatr Child Health
Journal subject:
PEDIATRIA
Year:
2012
Type:
Article
Affiliation country:
Australia