Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population.

Bye, Hannah; Prescott, Natalie J; Lewis, Cathryn M; Matejcic, Marco; Moodley, Loven; Robertson, Barbara; Rensburg, Christo van; Parker, M Iqbal; Mathew, Christopher G

Bye, Hannah; Prescott, Natalie J; Lewis, Cathryn M; Matejcic, Marco; Moodley, Loven; Robertson, Barbara; Rensburg, Christo van; Parker, M Iqbal; Mathew, Christopher G.

Affiliation

Bye H; Department of Medical and Molecular Genetics, King's College London, King's Health Partners, Guy's Hospital, London, United Kingdom.

Carcinogenesis ; 33(11): 2155-61, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22865593

Subject(s)

Carcinoma, Squamous Cell/genetics; Esophageal Neoplasms/genetics; Phosphoinositide Phospholipase C/genetics; Polymorphism, Single Nucleotide/genetics; Carcinoma, Squamous Cell/epidemiology; Carcinoma, Squamous Cell/pathology; Case-Control Studies; Core Binding Factor Alpha 2 Subunit/genetics; Cyclic Nucleotide Phosphodiesterases, Type 3/genetics; Cyclic Nucleotide Phosphodiesterases, Type 4; DNA/analysis; DNA/genetics; Esophageal Neoplasms/epidemiology; Esophageal Neoplasms/pathology; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Intracellular Signaling Peptides and Proteins/genetics; Male; Membrane Transport Proteins/genetics; Middle Aged; Neoplasm Staging; Prognosis; Real-Time Polymerase Chain Reaction; Risk Factors; South Africa/epidemiology

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Full text: 1 Database: MEDLINE Main subject: Esophageal Neoplasms / Carcinoma, Squamous Cell / Polymorphism, Single Nucleotide / Phosphoinositide Phospholipase C Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: Africa Language: En Journal: Carcinogenesis Year: 2012 Type: Article Affiliation country: United kingdom

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