HEC-cysteamine particles: influence of particle size, zeta potential, morphology and sulfhydryl groups on permeation enhancing properties.

Rahmat, Deni; Müller, Christiane; Shahnaz, Gul; Leithner, Katharina; Laffleur, Flavia; Khan, Mohammad Imran; Martien, Ronny; Bernkop Schnürch, Andreas

Rahmat, Deni; Müller, Christiane; Shahnaz, Gul; Leithner, Katharina; Laffleur, Flavia; Khan, Mohammad Imran; Martien, Ronny; Bernkop Schnürch, Andreas.

Affiliation

Rahmat D; Department of Pharmaceutical Technology, Institute of Pharmacy, Center for Chemistry and Biomedicine, Center for Molecular Biosciences, Leopold-Franzens-University Innsbruck, Innsbruck, Austria.

Drug Dev Ind Pharm ; 39(9): 1338-45, 2013 Sep.

Article in En | MEDLINE | ID: mdl-22901004

Subject(s)

Cellulose/analogs & derivatives; Cysteamine/chemistry; Enterocytes/metabolism; Excipients/chemistry; Fluorescent Dyes/metabolism; Sulfhydryl Compounds/chemistry; Tight Junctions/metabolism; Biological Transport; Caco-2 Cells; Cellulose/adverse effects; Cellulose/chemistry; Cellulose/ultrastructure; Chemical Phenomena; Cysteamine/adverse effects; Dextrans/metabolism; Electric Impedance; Excipients/adverse effects; Fluorescein-5-isothiocyanate/analogs & derivatives; Fluorescein-5-isothiocyanate/metabolism; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Microspheres; Models, Chemical; Nanoparticles/adverse effects; Nanoparticles/chemistry; Nanoparticles/ultrastructure; Particle Size; Permeability; Sulfhydryl Compounds/adverse effects; Surface Properties; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Sulfhydryl Compounds / Cellulose / Tight Junctions / Enterocytes / Cysteamine / Excipients / Fluorescent Dyes Limits: Humans Language: En Journal: Drug Dev Ind Pharm Year: 2013 Type: Article Affiliation country: Austria

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