A randomized, evaluator-blind, phase 2 study comparing the safety and efficacy of omadacycline to those of linezolid for treatment of complicated skin and skin structure infections.

Noel, Gary J; Draper, Michael P; Hait, Howard; Tanaka, S Ken; Arbeit, Robert D

Noel, Gary J; Draper, Michael P; Hait, Howard; Tanaka, S Ken; Arbeit, Robert D.

Affiliation

Noel GJ; Paratek Pharmaceuticals Inc., Boston, Massachusetts, USA. gjnoel14@gmail.com

Antimicrob Agents Chemother ; 56(11): 5650-4, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22908151

Subject(s)

Acetamides/administration & dosage; Anti-Bacterial Agents/administration & dosage; Aztreonam/administration & dosage; Methicillin-Resistant Staphylococcus aureus/drug effects; Minocycline/administration & dosage; Oxazolidinones/administration & dosage; Skin Diseases, Bacterial/drug therapy; Skin/drug effects; Staphylococcal Infections/drug therapy; Acetamides/adverse effects; Adolescent; Adult; Aged; Anti-Bacterial Agents/adverse effects; Aztreonam/adverse effects; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus/growth & development; Middle Aged; Minocycline/adverse effects; Minocycline/analogs & derivatives; Oxazolidinones/adverse effects; Placebos; Skin/microbiology; Skin Diseases, Bacterial/microbiology; Staphylococcal Infections/microbiology; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Skin / Staphylococcal Infections / Aztreonam / Skin Diseases, Bacterial / Oxazolidinones / Methicillin-Resistant Staphylococcus aureus / Acetamides / Minocycline / Anti-Bacterial Agents Type of study: Clinical_trials Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Antimicrob Agents Chemother Year: 2012 Type: Article Affiliation country: United States

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