Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma.

Gorantla, Bharathi; Bhoopathi, Praveen; Chetty, Chandramu; Gogineni, Venkateswara Rao; Sailaja, G S; Gondi, Christopher S; Rao, Jasti S

Gorantla, Bharathi; Bhoopathi, Praveen; Chetty, Chandramu; Gogineni, Venkateswara Rao; Sailaja, G S; Gondi, Christopher S; Rao, Jasti S.

Affiliation

Gorantla B; Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, IL 61605, USA.

Angiogenesis ; 16(1): 85-100, 2013 Jan.

Article in En | MEDLINE | ID: mdl-22956186

Subject(s)

Neovascularization, Pathologic/metabolism; Neuroblastoma/blood supply; Neuroblastoma/metabolism; Osteonectin/metabolism; Receptors, Notch/metabolism; Signal Transduction; Angiogenesis Inducing Agents/metabolism; Animals; Apoptosis/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Culture Media, Conditioned/pharmacology; Disease Models, Animal; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Endothelial Cells/pathology; Humans; Mice; Mice, Nude; Neuroblastoma/pathology; Phosphatidylinositol 3-Kinases/metabolism; Phosphorylation/drug effects; Proto-Oncogene Proteins c-akt; STAT3 Transcription Factor/metabolism; Signal Transduction/drug effects; Vascular Endothelial Growth Factor A/metabolism; Vascular Endothelial Growth Factor Receptor-2/metabolism

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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Osteonectin / Receptors, Notch / Neovascularization, Pathologic / Neuroblastoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Angiogenesis Journal subject: HEMATOLOGIA Year: 2013 Type: Article Affiliation country: United States

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