The design and proof of concept for a CD8(+) T cell-based vaccine inducing cross-subtype protection against influenza A virus.

Tan, Amabel C L; Deliyannis, Georgia; Bharadwaj, Mandvi; Brown, Lorena E; Zeng, Weiguang; Jackson, David C

Tan, Amabel C L; Deliyannis, Georgia; Bharadwaj, Mandvi; Brown, Lorena E; Zeng, Weiguang; Jackson, David C.

Affiliation

Tan AC; Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria, Australia.

Immunol Cell Biol ; 91(1): 96-104, 2013 Jan.

Article in En | MEDLINE | ID: mdl-23146941

Subject(s)

CD8-Positive T-Lymphocytes/immunology; Epitopes, T-Lymphocyte/immunology; Influenza A Virus, H1N1 Subtype/immunology; Influenza Vaccines/immunology; Influenza, Human/immunology; Administration, Intranasal; Animals; Cross Reactions; Epitopes, T-Lymphocyte/genetics; Epitopes, T-Lymphocyte/pharmacology; Female; HLA-A2 Antigen/genetics; HLA-A2 Antigen/immunology; Humans; Influenza A Virus, H1N1 Subtype/genetics; Influenza Vaccines/genetics; Influenza, Human/genetics; Influenza, Human/prevention & control; Lipopeptides/immunology; Lipopeptides/pharmacology; Male; Mice; Mice, Transgenic

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Full text: 1 Database: MEDLINE Main subject: Influenza Vaccines / CD8-Positive T-Lymphocytes / Epitopes, T-Lymphocyte / Influenza, Human / Influenza A Virus, H1N1 Subtype Limits: Animals / Female / Humans / Male Language: En Journal: Immunol Cell Biol Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Type: Article Affiliation country: Australia

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