Primary antiphospholipid syndrome in monozygotic twins.
Lupus
; 22(1): 92-4, 2013 Jan.
Article
in En
| MEDLINE
| ID: mdl-23154322
ABSTRACT
Monozygotic twins, 27 years old, with primary anti-phospholipid syndrome have been described. The first of the twins had obstetric morbidities (one miscarriage at 12 weeks and premature birth of a growth-restricted fetus at 27 weeks secondary to pre-eclampsia) and the second had venous thrombosis. Lupus anticoagulant was present in both and anti-cardiolipin antibodies were present in high titres when re-tested at appropriate intervals. Development of clinical features of APS in monozygotic twins points to an underlying genetic basis in the pathogenesis of anti-phospholipid syndrome.
Full text:
1
Database:
MEDLINE
Main subject:
Twins, Monozygotic
/
Antiphospholipid Syndrome
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Lupus
Journal subject:
REUMATOLOGIA
Year:
2013
Type:
Article
Affiliation country:
India