Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.

Cossu, Federica; Milani, Mario; Vachette, Patrice; Malvezzi, Francesca; Grassi, Serena; Lecis, Daniele; Delia, Domenico; Drago, Carmelo; Seneci, Pierfausto; Bolognesi, Martino; Mastrangelo, Eloise

Cossu, Federica; Milani, Mario; Vachette, Patrice; Malvezzi, Francesca; Grassi, Serena; Lecis, Daniele; Delia, Domenico; Drago, Carmelo; Seneci, Pierfausto; Bolognesi, Martino; Mastrangelo, Eloise.

Affiliation

Cossu F; Department of Biosciences, University of Milano, Milano, Italy.

PLoS One ; 7(11): e49527, 2012.

Article in En | MEDLINE | ID: mdl-23166698

Subject(s)

Inhibitor of Apoptosis Proteins/chemistry; Intracellular Signaling Peptides and Proteins/chemistry; Mitochondrial Proteins/chemistry; Molecular Mimicry; Apoptosis Regulatory Proteins; Biomimetics; Caspases/metabolism; Cell Line, Tumor; Crystallography, X-Ray; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; Mitochondrial Proteins/metabolism; Molecular Conformation; Molecular Docking Simulation; Protein Binding; Protein Multimerization; Proteolysis; X-Linked Inhibitor of Apoptosis Protein/chemistry

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Full text: 1 Database: MEDLINE Main subject: Molecular Mimicry / Mitochondrial Proteins / Intracellular Signaling Peptides and Proteins / Inhibitor of Apoptosis Proteins Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Type: Article Affiliation country: Italy

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