Fc gamma receptor IIIa polymorphisms in advanced colorectal cancer patients correlated with response to anti-EGFR antibodies and clinical outcome.

Calemma, Rosa; Ottaiano, Alessandro; Trotta, Anna Maria; Nasti, Guglielmo; Romano, Carmela; Napolitano, Maria; Galati, Domenico; Borrelli, Pasquale; Zanotta, Serena; Cassata, Antonino; Castello, Giuseppe; Iaffaioli, Vincenzo Rosario; Scala, Stefania

Calemma, Rosa; Ottaiano, Alessandro; Trotta, Anna Maria; Nasti, Guglielmo; Romano, Carmela; Napolitano, Maria; Galati, Domenico; Borrelli, Pasquale; Zanotta, Serena; Cassata, Antonino; Castello, Giuseppe; Iaffaioli, Vincenzo Rosario; Scala, Stefania.

Affiliation

Calemma R; Oncological Immunology, National Cancer Institute "G, Pascale", Naples, Italy.

J Transl Med ; 10: 232, 2012 Nov 21.

Article in En | MEDLINE | ID: mdl-23171437

Subject(s)

Antibodies, Monoclonal/therapeutic use; Colorectal Neoplasms/drug therapy; Colorectal Neoplasms/genetics; ErbB Receptors/immunology; Polymorphism, Single Nucleotide/genetics; Receptors, IgG/genetics; Adult; Aged; Aged, 80 and over; Alleles; Base Sequence; Colorectal Neoplasms/pathology; DNA Mutational Analysis; Disease-Free Survival; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Staging; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins p21(ras); Treatment Outcome; ras Proteins/genetics

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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Receptors, IgG / Polymorphism, Single Nucleotide / ErbB Receptors / Antibodies, Monoclonal Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: J Transl Med Year: 2012 Type: Article Affiliation country: Italy

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