Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreading.

Carr, Heather S; Morris, Christopher A; Menon, Sarita; Song, Eun Hyeon; Frost, Jeffrey A

Carr, Heather S; Morris, Christopher A; Menon, Sarita; Song, Eun Hyeon; Frost, Jeffrey A.

Affiliation

Carr HS; Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, USA.

Mol Cell Biol ; 33(3): 622-34, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23184663

Subject(s)

Cell Movement; Focal Adhesions/metabolism; Oncogene Proteins/metabolism; rac1 GTP-Binding Protein/metabolism; Animals; Blood Proteins/chemistry; Blood Proteins/metabolism; Breast Neoplasms/metabolism; Cell Line, Tumor; Cell Membrane/metabolism; Female; Gene Expression; Humans; Mice; Myosin Light Chains/metabolism; Oncogene Proteins/analysis; Phosphoproteins/chemistry; Phosphoproteins/metabolism; Phosphorylation; Proteasome Endopeptidase Complex/metabolism; Protein Isoforms/analysis; Protein Isoforms/metabolism; Protein Structure, Tertiary; cdc42 GTP-Binding Protein/metabolism; p21-Activated Kinases/metabolism; rac1 GTP-Binding Protein/genetics

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Full text: 1 Database: MEDLINE Main subject: Cell Movement / Oncogene Proteins / Rac1 GTP-Binding Protein / Focal Adhesions Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Mol Cell Biol Year: 2013 Type: Article Affiliation country: United States

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