Nimotuzumab promotes radiosensitivity of EGFR-overexpression esophageal squamous cell carcinoma cells by upregulating IGFBP-3.

Zhao, Lei; He, Li-Ru; Xi, Mian; Cai, Mu-Yan; Shen, Jing-Xian; Li, Qiao-Qiao; Liao, Yi-Ji; Qian, Dong; Feng, Zi-Zhen; Zeng, Yi-Xin; Xie, Dan; Liu, Meng-Zhong

Zhao, Lei; He, Li-Ru; Xi, Mian; Cai, Mu-Yan; Shen, Jing-Xian; Li, Qiao-Qiao; Liao, Yi-Ji; Qian, Dong; Feng, Zi-Zhen; Zeng, Yi-Xin; Xie, Dan; Liu, Meng-Zhong.

Affiliation

Zhao L; Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No 651 Dongfeng Road East, Guangzhou 510060, China.

J Transl Med ; 10: 249, 2012 Dec 11.

Article in En | MEDLINE | ID: mdl-23232108

Subject(s)

Antibodies, Monoclonal, Humanized/pharmacology; Carcinoma, Squamous Cell/metabolism; ErbB Receptors/metabolism; Esophageal Neoplasms/metabolism; Insulin-Like Growth Factor Binding Protein 3/metabolism; Radiation Tolerance; Up-Regulation; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell/pathology; Cell Line, Tumor; Esophageal Neoplasms/pathology; Humans; Immunohistochemistry

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Full text: 1 Database: MEDLINE Main subject: Radiation Tolerance / Esophageal Neoplasms / Carcinoma, Squamous Cell / Up-Regulation / Insulin-Like Growth Factor Binding Protein 3 / Antibodies, Monoclonal, Humanized / ErbB Receptors Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Transl Med Year: 2012 Type: Article Affiliation country: China

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