Hepatitis B virus X protein (HBx)-related long noncoding RNA (lncRNA) down-regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin.

Huang, Jin-feng; Guo, Ying-jun; Zhao, Chen-xi; Yuan, Sheng-xian; Wang, Yue; Tang, Guan-nan; Zhou, Wei-ping; Sun, Shu-han

Huang, Jin-feng; Guo, Ying-jun; Zhao, Chen-xi; Yuan, Sheng-xian; Wang, Yue; Tang, Guan-nan; Zhou, Wei-ping; Sun, Shu-han.

Affiliation

Huang JF; The Department of Medical Genetics, Second Military Medical University, Shanghai, China.

Hepatology ; 57(5): 1882-92, 2013 May.

Article in En | MEDLINE | ID: mdl-23239537

Subject(s)

Carcinoma, Hepatocellular/metabolism; Down-Regulation/physiology; Liver Neoplasms/metabolism; Neoplasm Metastasis/physiopathology; RNA, Long Noncoding/metabolism; Trans-Activators/metabolism; Vimentin/metabolism; Animals; Base Sequence; Carcinoma, Hepatocellular/physiopathology; Carcinoma, Hepatocellular/virology; Cell Movement/physiology; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic/physiology; Hepatitis B/complications; Humans; In Vitro Techniques; Liver Neoplasms/physiopathology; Liver Neoplasms/virology; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Middle Aged; Molecular Sequence Data; Survival Rate; Trans-Activators/genetics; Viral Regulatory and Accessory Proteins

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Full text: 1 Database: MEDLINE Main subject: Vimentin / Down-Regulation / Trans-Activators / Carcinoma, Hepatocellular / RNA, Long Noncoding / Liver Neoplasms / Neoplasm Metastasis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2013 Type: Article Affiliation country: China

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