The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle.

Holland, Andrew J; Fachinetti, Daniele; Zhu, Quan; Bauer, Manuel; Verma, Inder M; Nigg, Erich A; Cleveland, Don W

Holland, Andrew J; Fachinetti, Daniele; Zhu, Quan; Bauer, Manuel; Verma, Inder M; Nigg, Erich A; Cleveland, Don W.

Affiliation

Holland AJ; Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, California 92093, USA. a1holland@ucsd.edu

Genes Dev ; 26(24): 2684-9, 2012 Dec 15.

Article in En | MEDLINE | ID: mdl-23249732

Subject(s)

Cell Cycle/physiology; Centrosome/physiology; Protein Serine-Threonine Kinases/metabolism; Cell Division/genetics; Cell Line; Cell Proliferation; Enzyme Stability/physiology; Gene Targeting; Homeostasis/physiology; Humans; Protein Serine-Threonine Kinases/genetics; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Database: MEDLINE Main subject: Cell Cycle / Protein Serine-Threonine Kinases / Centrosome Limits: Humans Language: En Journal: Genes Dev Journal subject: BIOLOGIA MOLECULAR Year: 2012 Type: Article Affiliation country: United States

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