MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

Mellén, Marian; Ayata, Pinar; Dewell, Scott; Kriaucionis, Skirmantas; Heintz, Nathaniel

Mellén, Marian; Ayata, Pinar; Dewell, Scott; Kriaucionis, Skirmantas; Heintz, Nathaniel.

Affiliation

Mellén M; Laboratory of Molecular Biology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Cell ; 151(7): 1417-30, 2012 Dec 21.

Article in En | MEDLINE | ID: mdl-23260135

Subject(s)

Cerebellum/metabolism; Cytosine/analogs & derivatives; Epigenesis, Genetic; Methyl-CpG-Binding Protein 2/metabolism; 5-Methylcytosine/analogs & derivatives; Animals; Cerebellum/cytology; Chromatin/metabolism; Cytosine/metabolism; Humans; Mice; Mice, Knockout; Neuroglia/metabolism; Neurons/metabolism; Purkinje Cells/metabolism; Rett Syndrome/metabolism

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Full text: 1 Database: MEDLINE Main subject: Cerebellum / Cytosine / Epigenesis, Genetic / Methyl-CpG-Binding Protein 2 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Year: 2012 Type: Article Affiliation country: United States

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