EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia.

Szepietowska, Barbara; Zhu, Wanling; Czyzyk, Jan; Eid, Tore; Sherwin, Robert S

Szepietowska, Barbara; Zhu, Wanling; Czyzyk, Jan; Eid, Tore; Sherwin, Robert S.

Affiliation

Szepietowska B; Department of Internal Medicine and Endocrinology, Yale University School of Medicine, New Haven, Connecticut, USA.

Diabetes ; 62(4): 1282-8, 2013 Apr.

Article in En | MEDLINE | ID: mdl-23274893

Subject(s)

Ephrin-A5/pharmacology; Glutamic Acid/metabolism; Glutamine/metabolism; Hypoglycemia/metabolism; Receptor, EphA5/metabolism; Ventromedial Hypothalamic Nucleus/drug effects; Animals; Blood Glucose; Ephrin-A5/genetics; Ephrin-A5/metabolism; Epinephrine/blood; Epinephrine/metabolism; Gene Expression Regulation; Glucagon/blood; Glucagon/metabolism; Glucose/metabolism; Insulin/blood; Insulin/metabolism; Male; Norepinephrine/blood; Norepinephrine/metabolism; Rats; Rats, Sprague-Dawley; Receptor, EphA5/genetics; Ventromedial Hypothalamic Nucleus/metabolism

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Full text: 1 Database: MEDLINE Main subject: Ventromedial Hypothalamic Nucleus / Glutamic Acid / Receptor, EphA5 / Ephrin-A5 / Glutamine / Hypoglycemia Limits: Animals Language: En Journal: Diabetes Year: 2013 Type: Article Affiliation country: United States

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