NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.

Kummarapurugu, Apparao B; Fischer, Bernard M; Zheng, Shuo; Milne, Ginger L; Ghio, Andrew J; Potts-Kant, Erin N; Foster, W Michael; Soderblom, Erik J; Dubois, Laura G; Moseley, M Arthur; Thompson, J Will; Voynow, Judith A

Kummarapurugu, Apparao B; Fischer, Bernard M; Zheng, Shuo; Milne, Ginger L; Ghio, Andrew J; Potts-Kant, Erin N; Foster, W Michael; Soderblom, Erik J; Dubois, Laura G; Moseley, M Arthur; Thompson, J Will; Voynow, Judith A.

Affiliation

Kummarapurugu AB; Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.

J Biol Chem ; 288(7): 4681-91, 2013 Feb 15.

Article in En | MEDLINE | ID: mdl-23275341

Subject(s)

Isoprostanes/chemistry; NAD(P)H Dehydrogenase (Quinone)/physiology; Ozone/chemistry; Animals; Cell Line; Cysteine/genetics; Humans; Inflammation; Interleukin-8/metabolism; Lung/drug effects; Lung/metabolism; Mass Spectrometry/methods; Mice; Mice, Inbred C57BL; Models, Biological; NAD(P)H Dehydrogenase (Quinone)/metabolism; NF-kappa B/metabolism; Oxidation-Reduction

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Full text: 1 Database: MEDLINE Main subject: Ozone / NAD(P)H Dehydrogenase (Quinone) / Isoprostanes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: United States

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