Intact protein profiling in breast cancer biomarker discovery: protein identification issue and the solutions based on 3D protein separation, bottom-up and top-down mass spectrometry.

Bouchal, Pavel; Dvorakova, Monika; Scherl, Alexander; Garbis, Spiros D; Nenutil, Rudolf; Vojtesek, Borivoj

Bouchal, Pavel; Dvorakova, Monika; Scherl, Alexander; Garbis, Spiros D; Nenutil, Rudolf; Vojtesek, Borivoj.

Affiliation

Bouchal P; Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic. bouchal@chemi.muni.cz

Proteomics ; 13(7): 1053-8, 2013 Apr.

Article in En | MEDLINE | ID: mdl-23303686

Subject(s)

Biomarkers, Tumor/metabolism; Breast Neoplasms/metabolism; Neoplasm Proteins/isolation & purification; Neoplasm Proteins/metabolism; Proteomics/methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods; Amino Acid Sequence; Female; Humans; Molecular Sequence Data; Neoplasm Proteins/chemistry; Peptides/chemistry; Peptides/metabolism

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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms / Biomarkers, Tumor / Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Proteomics / Neoplasm Proteins Type of study: Diagnostic_studies / Guideline Limits: Female / Humans Language: En Journal: Proteomics Journal subject: BIOQUIMICA Year: 2013 Type: Article Affiliation country: Czech Republic

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