Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in &#916;F508 cystic fibrosis airway epithelium.

Oglesby, Irene K; Chotirmall, Sanjay H; McElvaney, Noel G; Greene, Catherine M

Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in ΔF508 cystic fibrosis airway epithelium.

Oglesby, Irene K; Chotirmall, Sanjay H; McElvaney, Noel G; Greene, Catherine M.

Affiliation

Oglesby IK; Respiratory Research Division, Department of Medicine, Education and Research Centre, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.

J Immunol ; 190(7): 3354-62, 2013 Apr 01.

Article in En | MEDLINE | ID: mdl-23436935

Subject(s)

Cystic Fibrosis Transmembrane Conductance Regulator/genetics; Cystic Fibrosis/genetics; Gene Expression Regulation; MicroRNAs/genetics; Respiratory Mucosa/metabolism; 3' Untranslated Regions; Adult; Base Sequence; Cell Line; Chlorides/metabolism; Cystic Fibrosis/metabolism; Cystic Fibrosis/microbiology; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism; Female; Gene Expression; Gene Expression Profiling; Gene Knockdown Techniques; Genotype; Humans; Intracellular Space/metabolism; Lung/metabolism; Lung/microbiology; Male; MicroRNAs/chemistry; MicroRNAs/metabolism; Pseudomonas aeruginosa/metabolism; Respiratory Mucosa/microbiology; Respiratory Mucosa/pathology

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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation / Cystic Fibrosis Transmembrane Conductance Regulator / Respiratory Mucosa / Cystic Fibrosis / MicroRNAs Limits: Adult / Female / Humans / Male Language: En Journal: J Immunol Year: 2013 Type: Article Affiliation country: Ireland

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