Macrophage migration inhibitory factor induces contractile and mitochondria dysfunction by altering cytoskeleton network in the human heart.

Preau, Sébastien; Montaigne, David; Modine, Thomas; Fayad, George; Koussa, Mohamed; Tardivel, Meryem; Durocher, Alain; Saulnier, Fabienne; Marechal, Xavier; Neviere, Remi

Preau, Sébastien; Montaigne, David; Modine, Thomas; Fayad, George; Koussa, Mohamed; Tardivel, Meryem; Durocher, Alain; Saulnier, Fabienne; Marechal, Xavier; Neviere, Remi.

Affiliation

Preau S; Departement de Physiologie (EA 4484), Faculte de Medecine, Universite Lille, IFR 114 (IMPRT), Lille, France.

Crit Care Med ; 41(7): e125-33, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23478658

Subject(s)

Cytoskeleton/drug effects; Macrophage Migration-Inhibitory Factors/pharmacology; Mitochondria, Heart/drug effects; Myocardium/metabolism; Myocytes, Cardiac/drug effects; AMP-Activated Protein Kinases/antagonists & inhibitors; Colchicine/pharmacology; Cytoskeleton/metabolism; Humans; In Vitro Techniques; Lactic Acid/metabolism; Mitochondria, Heart/metabolism; Muscle Contraction; Myocytes, Cardiac/metabolism; Nitrates/metabolism; Nitrites/metabolism; Paclitaxel/pharmacology; Pyrazoles/pharmacology; Pyrimidines/pharmacology; Troponin I/metabolism; Tubulin Modulators/pharmacology; Tumor Necrosis Factor-alpha/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Cytoskeleton / Macrophage Migration-Inhibitory Factors / Myocytes, Cardiac / Mitochondria, Heart / Myocardium Type of study: Clinical_trials Limits: Humans Language: En Journal: Crit Care Med Year: 2013 Type: Article Affiliation country: France

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google