Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery.
Bioorg Med Chem Lett
; 23(11): 3157-61, 2013 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-23632269
Full text:
1
Database:
MEDLINE
Main subject:
Quinolones
/
Calcitonin Gene-Related Peptide Receptor Antagonists
/
Amides
/
Indazoles
Limits:
Animals
/
Humans
Language:
En
Journal:
Bioorg Med Chem Lett
Journal subject:
BIOQUIMICA
/
QUIMICA
Year:
2013
Type:
Article
Affiliation country:
United States