Cardiotonic Agents/pharmacology; Heart Failure/drug therapy; Sodium-Potassium-Exchanging ATPase/metabolism; Amino Acid Sequence; Animals; Cardiotonic Agents/therapeutic use; Heart Failure/enzymology; Humans; Membrane Proteins/chemistry; Molecular Sequence Data; Oxidation-Reduction; Phosphoproteins/chemistry; Phosphorylation; Protein Kinase Inhibitors/pharmacology; Protein Kinase Inhibitors/therapeutic use; Protein Kinases/metabolism; Protein Processing, Post-Translational; Signal Transduction; Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors

ACE; AR; Ang II; GSH; Grx1; Heart failure; I(p); NADPH oxidase; NO; Na(+)­K(+) pump; ONOO(−); PKA; PKC; PKG; PP2A; Redox regulation; [Na(+)](i); adrenergic receptor; angiotensin II; angiotensin converting enzyme; cAMP; cyclic adenosine monophosphate, πGST, π isoform of glutathione S-transferase; electrogenic Na(+)­K(+) pump current; glutaredoxin 1; glutathione; intracellular Na(+) concentration; nicotinamide adenine dinucleotide phosphate-oxidase; nitric oxide; peroxynitrite; protein kinase A; protein kinase C; protein kinase G; protein phosphatase 2A; sGC; soluble guanylyl cyclase