Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas.

Xu, Shuo; Shao, Qian-Qian; Sun, Jin-Tang; Yang, Ning; Xie, Qi; Wang, Dong-Hai; Huang, Qi-Bing; Huang, Bin; Wang, Xin-Yu; Li, Xin-Gang; Qu, Xun

Xu, Shuo; Shao, Qian-Qian; Sun, Jin-Tang; Yang, Ning; Xie, Qi; Wang, Dong-Hai; Huang, Qi-Bing; Huang, Bin; Wang, Xin-Yu; Li, Xin-Gang; Qu, Xun.

Affiliation

Xu S; Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, China.

Neuro Oncol ; 15(9): 1160-72, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23737488

Subject(s)

5'-Nucleotidase/metabolism; Antigens, CD/metabolism; Apyrase/metabolism; Brain Neoplasms/immunology; CD4-Positive T-Lymphocytes/enzymology; Glioma/immunology; Immune Tolerance; Adenosine/metabolism; Brain Neoplasms/enzymology; Brain Neoplasms/metabolism; CD4-Positive T-Lymphocytes/immunology; Cell Line, Tumor; Glioma/enzymology; Glioma/metabolism; Humans; Lymphocytes, Tumor-Infiltrating/enzymology; Lymphocytes, Tumor-Infiltrating/immunology

Key words

CD39-CD73-adenosinergic immunosuppression; glioma microenvironment; infiltrating T lymphocytes; malignant glioma; synergic effect

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Apyrase / Brain Neoplasms / CD4-Positive T-Lymphocytes / Antigens, CD / 5'-Nucleotidase / Glioma / Immune Tolerance Type of study: Prognostic_studies Limits: Humans Language: En Journal: Neuro Oncol Journal subject: NEOPLASIAS / NEUROLOGIA Year: 2013 Type: Article Affiliation country: China

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google