Superior control of HIV-1 replication by CD8+ T cells targeting conserved epitopes: implications for HIV vaccine design.

Kunwar, Pratima; Hawkins, Natalie; Dinges, Warren L; Liu, Yi; Gabriel, Erin E; Swan, David A; Stevens, Claire E; Maenza, Janine; Collier, Ann C; Mullins, James I; Hertz, Tomer; Yu, Xuesong; Horton, Helen

Kunwar, Pratima; Hawkins, Natalie; Dinges, Warren L; Liu, Yi; Gabriel, Erin E; Swan, David A; Stevens, Claire E; Maenza, Janine; Collier, Ann C; Mullins, James I; Hertz, Tomer; Yu, Xuesong; Horton, Helen.

Affiliation

Kunwar P; Viral Vaccine Program, Seattle Biomedical Research Institute, Seattle, Washington, United States of America.

PLoS One ; 8(5): e64405, 2013.

Article in En | MEDLINE | ID: mdl-23741326

Subject(s)

Antigens, Viral/immunology; CD8-Positive T-Lymphocytes/immunology; Conserved Sequence; Epitopes, T-Lymphocyte/immunology; HIV Infections/immunology; HIV-1/immunology; Immunity, Cellular; Amino Acid Sequence; Antigens, Viral/genetics; CD8-Positive T-Lymphocytes/pathology; CD8-Positive T-Lymphocytes/virology; Epitope Mapping; Epitopes, T-Lymphocyte/genetics; Gene Expression; Genetic Heterogeneity; HIV Infections/pathology; HIV Infections/virology; HIV-1/growth & development; Homosexuality, Male; Humans; Male; Molecular Sequence Data; Viral Load/immunology; Virus Replication/immunology

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Full text: 1 Database: MEDLINE Main subject: HIV Infections / HIV-1 / Conserved Sequence / CD8-Positive T-Lymphocytes / Epitopes, T-Lymphocyte / Immunity, Cellular / Antigens, Viral Type of study: Risk_factors_studies Limits: Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Type: Article Affiliation country: United States

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