Direct cloning and tetramer staining to measure the frequency of intestinal gluten-reactive T cells in celiac disease.

Bodd, Michael; Ráki, Melinda; Bergseng, Elin; Jahnsen, Jørgen; Lundin, Knut E A; Sollid, Ludvig M

Bodd, Michael; Ráki, Melinda; Bergseng, Elin; Jahnsen, Jørgen; Lundin, Knut E A; Sollid, Ludvig M.

Affiliation

Bodd M; Department of Immunology, Centre for Immune Regulation, Oslo University Hospital-Rikshospitalet, Oslo, Norway.

Eur J Immunol ; 43(10): 2605-12, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23775608

Subject(s)

CD4-Positive T-Lymphocytes/immunology; Celiac Disease/immunology; Intestines/immunology; Biopsy; Celiac Disease/diagnosis; Cell Separation; Clone Cells; Flow Cytometry; GTP-Binding Proteins/immunology; Glutens/immunology; HLA-DQ Antigens/metabolism; Humans; Immunodominant Epitopes/immunology; Immunoglobulin A/blood; Intestines/pathology; Peptide Fragments/immunology; Protein Binding; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases/immunology

Key words

Celiac disease; Frequency; Gluten-specific T cells; Tetramer

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Full text: 1 Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Celiac Disease / Intestines Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Eur J Immunol Year: 2013 Type: Article Affiliation country: Norway

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