Interaction between basic residues of Epstein-Barr virus EBNA1 protein and cellular chromatin mediates viral plasmid maintenance.

Kanda, Teru; Horikoshi, Naoki; Murata, Takayuki; Kawashima, Daisuke; Sugimoto, Atsuko; Narita, Yohei; Kurumizaka, Hitoshi; Tsurumi, Tatsuya

Kanda, Teru; Horikoshi, Naoki; Murata, Takayuki; Kawashima, Daisuke; Sugimoto, Atsuko; Narita, Yohei; Kurumizaka, Hitoshi; Tsurumi, Tatsuya.

Affiliation

Kanda T; Division of Virology, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya 464-8681, Japan. tkanda@aichi-cc.jp

J Biol Chem ; 288(33): 24189-99, 2013 Aug 16.

Article in En | MEDLINE | ID: mdl-23836915

Subject(s)

Amino Acids, Basic/metabolism; Chromatin/metabolism; Epstein-Barr Virus Nuclear Antigens/chemistry; Epstein-Barr Virus Nuclear Antigens/metabolism; Herpesvirus 4, Human/metabolism; Plasmids/metabolism; Amino Acid Sequence; Amino Acid Substitution/genetics; Chromosomes, Human/metabolism; HeLa Cells; Humans; Molecular Sequence Data; Mutant Proteins/metabolism; Mutation/genetics; Nucleosomes/metabolism; Peptides/chemistry; Peptides/metabolism; Protein Binding; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins/metabolism

Key words

Amino Acid; Chromosomes; Confocal Microscopy; DNA Viruses; EBNA1; Episome; Epstein-Barr Virus; Fluorescence; Nucleosome; Site-directed Mutagenesis

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Full text: 1 Database: MEDLINE Main subject: Plasmids / Chromatin / Herpesvirus 4, Human / Epstein-Barr Virus Nuclear Antigens / Amino Acids, Basic Limits: Humans Language: En Journal: J Biol Chem Year: 2013 Type: Article Affiliation country: Japan

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