RNA structural motif recognition based on least-squares distance.
RNA
; 19(9): 1183-91, 2013 Sep.
Article
in En
| MEDLINE
| ID: mdl-23887146
ABSTRACT
RNA structural motifs are recurrent structural elements occurring in RNA molecules. RNA structural motif recognition aims to find RNA substructures that are similar to a query motif, and it is important for RNA structure analysis and RNA function prediction. In view of this, we propose a new method known as RNA Structural Motif Recognition based on Least-Squares distance (LS-RSMR) to effectively recognize RNA structural motifs. A test set consisting of five types of RNA structural motifs occurring in Escherichia coli ribosomal RNA is compiled by us. Experiments are conducted for recognizing these five types of motifs. The experimental results fully reveal the superiority of the proposed LS-RSMR compared with four other state-of-the-art methods.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
RNA
/
Nucleotide Motifs
Type of study:
Prognostic_studies
Language:
En
Journal:
RNA
Journal subject:
BIOLOGIA MOLECULAR
Year:
2013
Type:
Article
Affiliation country:
China