Life without TTP: apparent absence of an important anti-inflammatory protein in birds.

Lai, Wi S; Stumpo, Deborah J; Kennington, Elizabeth A; Burkholder, Adam B; Ward, James M; Fargo, David L; Blackshear, Perry J

Lai, Wi S; Stumpo, Deborah J; Kennington, Elizabeth A; Burkholder, Adam B; Ward, James M; Fargo, David L; Blackshear, Perry J.

Affiliation

Lai WS; Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina;

Am J Physiol Regul Integr Comp Physiol ; 305(7): R689-700, 2013 Oct 01.

Article in En | MEDLINE | ID: mdl-23904106

Subject(s)

Avian Proteins/deficiency; Chickens/metabolism; Immunity, Innate; Inflammation/prevention & control; Tristetraprolin/deficiency; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/metabolism; Amino Acid Sequence; Animals; Avian Proteins/genetics; Base Sequence; Cattle; Cell Line; Chickens/genetics; Chickens/immunology; Databases, Genetic; Gene Expression Regulation/drug effects; High-Throughput Nucleotide Sequencing; Humans; Immunity, Innate/drug effects; Inflammation/genetics; Inflammation/immunology; Inflammation/metabolism; Kinetics; Lipopolysaccharides/pharmacology; Mice; Molecular Sequence Data; Phylogeny; RNA, Messenger/metabolism; Reptiles/genetics; Reptiles/immunology; Reptiles/metabolism; Reptilian Proteins/genetics; Reptilian Proteins/metabolism; Sequence Analysis, DNA; Time Factors; Transfection; Tristetraprolin/genetics; Tristetraprolin/metabolism

Key words

AU-rich elements; innate immunity; mRNA turnover; tristetraprolin; zinc finger proteins

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Full text: 1 Database: MEDLINE Main subject: Chickens / Avian Proteins / Tristetraprolin / Immunity, Innate / Inflammation Type of study: Prognostic_studies Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2013 Type: Article

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