Double minute chromosomes in glioblastoma multiforme are revealed by precise reconstruction of oncogenic amplicons.

Sanborn, J Zachary; Salama, Sofie R; Grifford, Mia; Brennan, Cameron W; Mikkelsen, Tom; Jhanwar, Suresh; Katzman, Sol; Chin, Lynda; Haussler, David

Sanborn, J Zachary; Salama, Sofie R; Grifford, Mia; Brennan, Cameron W; Mikkelsen, Tom; Jhanwar, Suresh; Katzman, Sol; Chin, Lynda; Haussler, David.

Affiliation

Sanborn JZ; Authors' Affiliations: Five3 Genomics, LLC; Center for Biomolecular Science and Engineering, University of California; Howard Hughes Medical Institute, Santa Cruz, California; Human Oncology & Pathogenesis Program and Department of Neurosurgery; Cytogenetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York; Departments of Neurology & Neurosurgery, Henry Ford Hospital, Detroit, Michigan; and Department of Genomic Medicine, The University of T

Cancer Res ; 73(19): 6036-45, 2013 Oct 01.

Article in En | MEDLINE | ID: mdl-23940299

Subject(s)

Biomarkers, Tumor/genetics; Brain/metabolism; Chromosome Aberrations; Chromosomes, Human/genetics; Genome, Human; Glioblastoma/genetics; Brain Neoplasms; Case-Control Studies; Chromosome Mapping; Cohort Studies; Gene Dosage; Humans; In Situ Hybridization, Fluorescence; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA

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Full text: 1 Database: MEDLINE Main subject: Brain / Biomarkers, Tumor / Genome, Human / Chromosome Aberrations / Chromosomes, Human / Glioblastoma Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Cancer Res Year: 2013 Type: Article

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